Peptide nucleic acid coupled polypeptide ile Glu Gly Arg PNA (s-2222) | BOC Leu Gly Arg PNA

Peptide nucleic acid coupled peptide Ile-Glu-Gly-Arg-pNA (S-2222)|Boc-Leu-Gly-Arg-PNA

Peptide nucleic acid (PNA,peptidenucleicacid) It's a kind of DNA Analogues . The molecule is characterized by neutral peptide amides 2- Amino ethyl glycine bond replaces DNA Pentose phosphate diester bond skeleton in , The rest are related to DNA identical .PNA Can pass Watson-Crick The form of base pairing is recognized and combined DNA or RNA Sequence , Form a stable double helix structure .

Peptide nucleic acid has many advantages , There are mainly :

1. It can be synthesized by units ;

2. Anti nuclease and protease degradation ;

1. Good water solubility and stability ;
2. The sequence length ratio required for peptide nucleic acid DNA short ;
3. Peptide nucleic acid and DNA The combination requires only a low salt reaction environment .

 

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Small make up axc,2022.07.20