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中国矿大团队,开发集成多尺度深度学习模型,用于 RNA 甲基化位点预测
2022-06-23 13:51:00 【智源社区】
研究表明,通过转录后 RNA 修饰进行的表观转录组调控,对于所有种类的 RNA 都是必不可少的。准确识别 RNA 修饰,对于了解其目的和调控机制至关重要;并且,这些信息将可能对众多人类疾病的研究带来巨大帮助。然而,识别 RNA 修饰位点的传统实验方法相对复杂、耗时且费力。
中国矿业大学的研究人员提出了一种集成多尺度深度学习预测器(EMDLP),以 NLP 和 DL 方式识别 RNA 甲基化位点。它有机地结合了扩张卷积和双向 LSTM(BiLSTM),有助于更好地利用局部和全局信息进行站点预测。
该研究以「EMDLP: Ensemble multiscale deep learning model for RNA methylation site prediction」为题,于 2022 年 6 月 8 日发布在《BMC Bioinformatics》。

EMDLP 服务器:
http://www.labiip.net/EMDLP/index.php
论文链接:
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-022-04756-1
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