Nucleic acid modified metal organic framework drug carrier | pcn-223 metal organic framework encapsulated ad adamantane | zif-8 encapsulated adriamycin (DOX)

Nucleic acid modified metal organic framework drug carrier ;PCN-223 Metal organic skeleton loading Ad Adamantane ;ZIF-8 Encapsulated adriamycin (DOX)

Usually , The drug is loaded into... By in situ encapsulation or post synthesis modification strategy MOFs in . The former is a relatively simple method , It is suitable for heat stable drugs to overcome the premature release of drugs . The latter provides a more benign environment to avoid damaging drug molecules . With MOF Development of Chemistry , Has explored a series of MOFs As a promising candidate carrier in this field .

ZIF-8 Encapsulated adriamycin (DOX) Introduction to

Use metal - Organic framing materials ZIF-8 Wrap molybdenum disulfide (MoS2) Nano tablets and adriamycin (DOX) Build an acid that can pass pH And near infrared (NIR) Light triggered tumor Chemistry / Photothermal system , 

Method ： First , The particle size was prepared by hydrothermal reaction and ultrasonic treatment ～100nm, Thickness is 0.3～1.4nm Of MoS2 Nanosheets . then , Through one-step process, acid degradable metals - Organic framework ZIF-8 Wrapped in the prepared MoS2 On nano chip , And load drugs at the same time DOX, Form load DOX Of ZIF-8 The parcel MoS2 Nanocomposites (DOX/[email protected]).

Liposome modified iron-based metal organic framework nano drugs [email protected]

Cyclodextrin metal organic framework materials (CD-MOFs) Containing emodin

Cyclodextrin metal organic framework materials (CD-MOFs) Loaded with quercetin

Ferulic acid / potassium /β- Cyclodextrin metal organic framework inclusion complex (FA/K/β-CD/MOF),

Cyclodextrin metal organic framework materials (CDMOFs) Loading sucralose

Cyclodextrin metal organic framework materials (CDMOFs) Loading diflunisal

Cyclodextrin metal organic framework materials (CDMOFs) Loaded omeprazole (OME)

Metal organic framework of folic acid ligand MOFs Material load 5- Fluorouracil

Metal organic framework of folic acid ligand MOFs Material loaded sidabelamine

Metal organic framework of folic acid ligand MOFs Material loaded paclitaxel

Metal organic framework of folic acid ligand MOFs Material loaded adriamycin

Metal organic framework of folic acid ligand MOFs The material is loaded with daunorubicin and other drugs

The above information comes from Xiaobian axc,2022.06.15