5,10,15,20-tetra (3,5-dimethoxyphenyl) porphyrin ((tdmpp) H2) /2-nitro-5,10,15,20-tetra (3,5-dimethoxyphenyl) porphyrin copper (no2tdmpp) Cu) supplied by Qiyue

5,10,15,20- Four (3,5- Dimethoxyphenyl ) porphyrin ((TdmPP)H2) The preparation method of

A return condensing pipe is installed at the 、 Constant pressure dropping funnel 、 Mechanical mixer 250mL In a three necked flask , Join in 0.03mol3,5- Dimethoxybenzaldehyde and 100mL Propionic acid , Stir and heat to reflux , Then add slowly through constant pressure dropping funnel 0.03mol(2mL) Freshly steamed pyrrole and 20mL Propionic acid mixture , Continue stirring and refluxing 60min after , Stop heating , Let it cool slightly , Add 150mL methanol , Put it in the refrigerator and let it stand overnight , Suction filtration , Wash the solid with methanol until it is colorless . Then the crude product is made into a saturated chloroform solution , Heating methanol for recrystallization . Suction filtration , Vacuum drying of solids . Bright purple crystal 5,10,15,20- Four (3,5- Dimethoxyphenyl ) porphyrin (TdmPP)H21.20g, Yield 18.7%.

 

 2- Nitro -5,10,15,20- Four (3,5- Dimethoxyphenyl ) Porphyrin copper (NO2TdmPP)Cu) The preparation method of

A return condensing pipe is installed at the 、 Constant pressure dropping funnel 、 Mechanical mixer 250mL In a three necked flask , Join in 320mg5,10,15,20- Four (3,5- Dimethoxyphenyl ) porphyrin ,460mg Copper acetate ,120mL Chloroform ,3mL methanol ,3mL Glacial acetic acid , stay 50-60°C Heat and stir in a water bath 3h,TLC No... Detected 5,10,15,20- Four (3,5- Dimethoxyphenyl ) Porphyrins exist , Then add 214mg Copper nitrate and 7mL Acetic anhydride , The reaction temperature drops to 40-50°C, Keep reacting 2.5h, The reaction is basically completed . The reaction mixture is washed with water 、 Alkali washing 、 After washing , Dry with anhydrous magnesium sulfate , Concentrated to saturation , Using neutral alumina as stationary phase , Dichloromethane as a drenching agent , Carry out column chromatography separation and purification , Collect the main color bands , Steam until dry , Purple solid 2- Nitro -5,10,15,20- Four (3,5- Dimethoxyphenyl ) Porphyrin copper (NO2TdmPP)Cu)300mg, The yield is 83.0%.

  Porphyrin catalogue ：
   Four (4- Nitrophenyl ) porphyrin T (4-NO2P)P
Four (2- Aminophenyl ) porphyrin T(2-NH2P)P
Four (4- Aminophenyl ) porphyrin T(4-NH2P)P
Four (3,4- Methylene dioxyphenyl ) porphyrin T(MDOP)P
Four (2- Acetoxyphenyl ) porphyrin T(2-AOP)P
Four (4- Acetoxyphenyl ) porphyrin T(4-AOP)P
Four (4- Acetylaminophenyl ) porphyrin T(4-AAP)P
Four (4- Nicotinyl aminophenyl ) porphyrin T(4-NAP)P
Four (4- Isonicotinyl aminophenyl ) porphyrin T(4-IAP)P
Four (4- Pentaalkoxyphenyl ) porphyrin T(4-C5H11OP)P
Four (4- Octanoxyphenyl ) porphyrin T(4C8H17OP)P
5-(3- Acetoxyphenyl )-10,15,20- Three p-bromophenyl porphyrins
5-(4- Benzoyloxyphenyl )-10,15,20- Triprop chlorophenyl porphyrin
5-[4-(3- Nitrobenzoyl oxide ) phenyl ]-10,15,20- Triprop chlorophenyl porphyrin
5-(2- Bromopropoxy phenyl )-10,15,20- Trichlorophenyl porphyrin
5-{2-[( Benzo -15- crown -5)-4- amino ] Propoxy phenyl }-10,15,20- Trichlorophenyl porphyrin
5- phenyl -10,15,20- 3、 ... and (4- Phenyl sulfonate ) porphyrin TPPS3
5-(3,4- Dihydroxy -5- Phenyl sulfonate )-10,15,20- 3、 ... and (4- Phenyl sulfonate ) porphyrin
5- Phenyl p-sulfonate -10,15,20- 3、 ... and (4- Sulfonyl -5'- Fluorourea midridine phenyl porphyrin
5-[β-2-(N- Imidazolyl ) Glutamine ] phenyl -10,15,20- 3、 ... and [(α α α-2- Trimethyl acetamide ) phenyl ] porphyrin
5-{α-2-[4-[12-(1- Imidazole ) Dodecyl ] Carbamoyl ]-2,2- Dimethylbutyrylamino } phenyl -10,15,20- 3、 ... and (α α α-2- Trimethyl acetamide phenyl ) porphyrin
5-( Benzo -15- crown -5 )-10,15,20- Three p-dimethylaminophenyl porphyrins
5-( Benzo -15- crown -5 )-10,15,20- Trimethylammonium phenyl porphyrin iodide

This article comes from Xiaobian axc.2022.02.14