Research reagents Cholesterol-PEG-Maleimide, CLS-PEG-MAL, Cholesterol-PEG-Maleimide

I. Details

1. Name

Chinese: Cholesterol-Polyethylene Glycol-Maleimide (MW: 3400)

English: CLS-PEG-MAL

Cholesterol-PEG-Maleimide

2. Properties

Molecular weight: 3.4k, other molecular weights of Cholesterol-PEG-Maleimide can be customized (5k, 2k, 1k, etc.).Quality control at 95%+.

Physical Properties: Solid or liquid depending on molecular weight.Soluble in conventional solutions and most organic solvents.

Storage conditions: Freeze at -20°.Store away from light and dry.

Uses: For scientific research, drug release, nanotechnology and new material research, cell culture.Active compounds in the research of ligands, peptide synthesis supports, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings.

Reminder: In order to achieve the best use effect, the material should always be kept in a dry low temperature condition.Avoid frequent thawing and freezing.

Second, structural formula

Three, description

CLS-PEG-MAL is one of the maleimide-modified PEGs, which can be used to modify proteins, antibodies, peptides, etc.Maleimides can react with sulfhydryl groups to form stable thioether bonds.

The two ends of the CLS-PEG-MAL molecular chain are cholesterol and maleimide groups.It is a linear heterobifunctional PEG reagent and a lipophilic lipid PEG conjugate with good water solubility.Maleimide and sulfhydryl easily form stable sulfide bonds between pH 6.5 and 7.5.Cholesterol-functionalized polyethylene glycol is a lipophilic lipid PEG conjugate with good water solubility.Cholesterol can regulate the fluidity of phospholipid bilayers, reducing membrane permeability and drug leakage.It also has a protective effect on the oxidation of phospholipids.CLS-PEG-MAL can be used to make liposomes to shorten the cycle time of encapsulated drugs, and it can also be used in non-viral transfection reagents.

Four, related products

Cholesterol-PEG-Maleimide, Cholesterol-PEG-Maleimide, CLS-PEG-MAL, MW: 20000

Cholesterol-PEG-Maleimide, Cholesterol-PEG-Maleimide, CLS-PEG-MAL, MW: 10000

Cholesterol-PEG-Maleimide, Cholesterol-PEG-Maleimide, CLS-PEG-MAL, MW: 5000

Cholesterol-PEG-Maleimide, Cholesterol-PEG-Maleimide, CLS-PEG-MAL, MW: 3400

Cholesterol-PEG-Maleimide, Cholesterol-PEG-Maleimide, CLS-PEG-MAL, MW: 1000

The above information about CLS-PEG-MAL is provided by Shaanxi Xinyan Bomei Biotechnology Co., Ltd. ZH, please consult for details