Study on gene targeting preparation of tissue plasminogen activator loaded on albumin nano ultrasonic microbubbles

Today, the content I want to share with you is Albumin nano - Ultrasound microbubbles carry tissue plasminogen activator gene targeting Scientific research content , Let's study together ！

Albumin nano - Preparation method of ultrasound microbubble loaded tissue plasminogen activator gene targeting ：

An albumin nano - Ultrasound microbubble loaded tissue plasminogen activator gene targeting system , Including load reorganization tPA Gene plasmid albumin nanoparticles and sucrose albumin ultrasound microbubbles ;

The preparation method comprises the following steps :

Prepare loaded recombinant tPA Gene plasmid albumin nanoparticles ;2) Prepare sucrose albumin ultrasound microbubbles ;3) Load recombination tPA Albumin nanoparticles were prepared by ultrasound microbubbles of gene plasmid albumin nanoparticles and sucrose albumin - Ultrasound microbubble loaded tissue plasminogen activator gene targeting system . The invention constructs and recombines tPA Gene plasmid and albumin nanoparticles and ultrasound microbubbles were selected as carriers , It can be effectively and continuously transduced into body cells tPA The birth of , And it's safe , Noninvasive .

Related products

HER2-2-ME-BSANPs Monoclonal antibody specific 2- Methoxyestradiol albumin nanoparticles

resist HER2/neu Receptor peptide like modified paclitaxel self protein nanoparticles

Ginsenoside albumin nanoparticles

Chitosan modified albumin nanoparticles

mPEG-HSA Polyethylene glycol human serum albumin nanoparticles

HSA-Pc NPs Human serum albumin (HSA) Encapsulated phthalocyanine molecular nanoparticles

The parcel DNA And photosensitizer Ce6 Albumin nanoparticles

Gossypol albumin nanoparticles

Lapatinib albumin nanoparticles

Photosensitizer chlorin e6(chlorin e6,Ce6) Modified human serum albumin

Bovine serum albumin - Melamine conjugate modification

Glutaraldehyde modified sulfamethazine (SM2) With bovine serum albumin (BSA) coupling

Epidermal growth factor (EGF) Coupled bovine serum albumin nanocarrier

Ruixi YWX.2022.7.25