liftOver进行基因组坐标转换

Liftover是UCSC中用于基因组版本之间转换的一个工具，既可以做某一物种内基因组版本的转换，还可以做物种间基因组版本的转换。

1 网页转换

http://genome.ucsc.edu/cgi-bin/hgLiftOver
 

2. linux本地运行

### 下载软件
wget http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/liftOver

### 下载相关文件（hg38和hg19坐标转换）
wget http://hgdownload.cse.ucsc.edu/goldenPath/hg19/liftOver/hg19ToHg38.over.chain.gz 
wget http://hgdownload.cse.ucsc.edu/goldenPath/hg38/liftOver/hg38ToHg19.over.chain.gz

### 执行转换
liftOver access-5k-mappable.hg19.bed hg19ToHg38.over.chain.gz access-5k-mappable.hg38.bed unMapped.txt

# access-5k-mappable.hg19.bed 需要转化的bed
# access-5k-mappable.hg38.bed 转化后的bed