Doxorubicin loaded on metal organic framework MIL-88 DOX | folic acid modified uio-66-nh2 doxorubicin loaded [email

Metal organic frameworks MIL-88 Loading adriamycin DOX| Folic acid modification UiO-66-NH2 Loading adriamycin [email protected] Nanoparticles

Metal - Organic skeleton (MOFs) It is a kind of highly ordered crystalline porous coordination polymer (PCPs).MOFs It has clear structure 、 High specific surface area and porosity 、 The aperture is adjustable 、 Easy chemical functionalization and other advantages , It is considered as a kind of promising nano drug carrier .

With UiO-66 The organometallic framework as a carrier for the opioid hydrochloride (DOX) After loading and then using the composite decoration (Post-Syn-theticModification) Method to get [email protected] and [email protected] Nanoparticles ,, Prepare and load in one pot DOX Of UiO-66([email protected]), Modified with diethylenetriamine [email protected] To prepare [email protected], Later, folic acid (FA) Yes [email protected], Carry out surface chemical modification , structure [email protected]

COF-5 load 5-Fu(5- Fluorouracil )

Covalent organic framework materials COF-105 Loaded methotrexate

COF-102 Loading adriamycin (DOX)

COF-300 Loading taxol

CCOF-1 Containing ibuprofen

Covalent organic framework materials COF-5 Camptothecin loaded

COF-105 Loading curcumin

COF-102 It contains gambogic acid

COF-300 Loaded carbenicillin

The above information comes from Xiaobian axc,2022.06.15