Study on PEGylation of lumiprobe and PEG linker - iodine-peg3-acid

AI Meijie Lumiprobe  PEGylation and  PEG  Joint 丨 iodine -PEG3- acid background ：

Contains carboxylic acid  (COOH)  Groups and alkyl iodine functional groups .

Alkyl iodine is a powerful alkylating agent . They react with a variety of nucleophiles , Para mercaptan group 、 amine 、 Alcohols and phenols are very active .

The molecule allows the passage of flexible and hydrophilic  PEG3  Joints are subjected to various conjugations .

 

AI Meijie  Lumiprobe  iodine -PEG3- acid chemical property ：

form ：  White to light brown oil

Molecular weight ：332.13

Molecular formula ：C 9 H 17 IO 5

solubility ： Good water 、J Organic solvent

The quality control ：NMR 1 H, HPLC-MS (95%)

Storage conditions ： Store ： stay  -20°C  Keep away from light . transport ： At room temperature for  3  Zhou . Avoid prolonged exposure to light . dry .

AI Meijie  Lumiprobe  iodine -PEG3- acid Related research ：

Alkyne -PEG2- Iodide

Bifunctional reactive cross linker , Contains for click chemistry or  Sonogashira  Coupled terminal alkynyl , And reactive alkyl iodine groups .

Alkyne -PEG3- Iodide

Having alkyne and iodide functional groups  PEG3, A reactive and hydrophilic linker for alkylation and click chemistry .

chlorine -PEG3- Azide

PEG3  Azide chloride contains a reactive halogen atom and an azide group , Used to click on chemical reactions . It can also be used as a protected amino equivalent .

iodine -PEG3- Azide

Iodo-PEG3-Azide  It is a dual function connector , It has highly reactive alkylated halogen functional groups and is used for  Click chemistry / Staudinger ligation  Azido group of .

iodine -PEG3- Iodide

Based on the same bifunction with halogen reaction group  PEG3  The linker can be used for the crosslinking of nucleophiles .