Lumiprobe phosphide hexaethylene phosphide specification

AI Meijie  Lumiprobe  Spacer phosphide  18（ Hexaethylene glycol phosphorous amide ） It is a kind of imino reagent for oligonucleotide synthesis . It provides a long hydrophilic connector , Can be used for synthesis  Scorpion  type  qPCR  probe , Used to separate biotin from oligonucleotide chain , And for other applications that require modifiers and spatial separation of oligonucleotides .

AI Meijie  Lumiprobe Hexaethylene glycol phosphorous amide chemical property ：

form ：  colourless / Yellowish oil

Molecular weight ： 784.92

CAS Number ： 125607-09-2

Molecular formula ： C 42 H 61 N 2 O 10 P

solubility ：  It performs well in most organic solvents

The quality control ：NMR 1 H、31 P、HPLC-MS (95%), Oligonucleotide synthesis test

Storage conditions ： Store ： stay  -20°C  Keep away from light . transport ： At room temperature for  3  Zhou . Avoid prolonged exposure to light . dry .

Details of oligonucleotide synthesis

Coupling conditions ： Standard coupling , Same as normal nucleobase

Deprotection condition ： Same as the protected nucleobase

AI Meijie  Lumiprobe  Hexaethylene glycol phosphorous amide Related research ：

1、 Alkyne  CPG 1000A

It is used to synthesize alkyne modified  DNA/RNA  Controllable pore glass solid support （ Aperture  1000 Å）, Used to synthesize with  3'- Alkyne modified long modified oligonucleotides .

2、DusQ1 Phosphorous amide