当前位置:网站首页>UiO-66-COOH装载苯达莫司汀|羟基磷灰石( HA) 包裹MIL-53(Fe)纳米粒子|装载黄芩苷锰基金属有机骨架材料
UiO-66-COOH装载苯达莫司汀|羟基磷灰石( HA) 包裹MIL-53(Fe)纳米粒子|装载黄芩苷锰基金属有机骨架材料
2022-07-03 13:24:00 【qiyueshengwu】
UiO-66-COOH装载苯达莫司汀;羟基磷灰石( HA) 包裹MIL-53(Fe)纳米粒子;|装载黄芩苷锰基金属有机骨架材料;
MOFs具有独特的性质,如高度有序的结构、高比表面积和大孔容,使其能够在其外表面或开放通道上吸附功能分子,并将这些分子困在骨架内。此外,功能分子可以通过一锅法合成或合成后修饰,通过共价键结合到MOFs中。主要有四种先进策略可使具有生物应用剂的MOFs功能化,包括:表面吸附、孔包封、共价结合和功能分子作为为构建模块。
UiO-66-COOH装载苯达莫司汀的介绍
以金属Zr离子为中心,分别与不同的有机配体合成了三种金属有机框架(MOFs)载体(UiO-66,UiO-66-NH2,UiO-66-COOH),并采用浸渍法装载苯达莫司汀,三种MOFs载体均成功载入苯达莫司汀,且三种MOFs载体载药前后晶型结构不发生改变,热稳定性较强,其中UiO-66-COOH的载药能力优于UiO-66-NH2和UiO-66。

金属有机骨架MOF-5装载氨苯蝶啶([email protected])
MOF-808金属有机骨架装载5-Fu(5-氟尿嘧啶)
CD-MOF环糊精-金属有机骨架包载甲氨蝶呤
MOF-199负载阿霉素(DOX)
金属有机骨架MOF-53装载紫杉醇
MOF-5包载布洛芬
Eu-MOF负载喜树碱
铽基金属有机骨架材料Tb-MOF装载姜黄素
镝基金属有机骨架材料Dy-MOF包载藤黄酸
Pd-MOF负载羧苄西林
Bio-MOF-11装载MTX 甲氨蝶呤
以上资料来自小编axc,2022.06.15
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