DSPE-PEG-COOH CAS: 1403744-37-5 Phospholipid-polyethylene glycol-carboxy lipid PEG conjugate

I. Details

1. Name

Chinese: Phospholipid-Polyethylene Glycol-Carboxyl (MW: 3400)

English: DSPE-PEG-COOH

Cholesterol-PEG-Thiol

CAS: 1403744-37-5

2. Properties

DSPE-PEG-COOH molecular weight: 3.4k, other molecular weights can be customized (5k, 2k, 1k, etc.).Quality control at 95%+.

Physical Properties: Solid or liquid depending on molecular weight.Soluble in conventional solutions and most organic solvents.

Storage conditions: Freeze at -20°.Store away from light and dry.

Usage: For scientific research, drug release, nanotechnology and new material research, cell culture.

Reminder: In order to achieve the best use effect, the material should always be kept in a dry low temperature condition.Avoid frequent thawing and freezing.

Second, structural formula

Three, description

DSPE-PEG-COOH is one of the reactive phospholipid PEG conjugates that can react with primary amine groups.DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is a highly hydrophobic 18-carbon phospholipid, on the other hand, a PEG linker provides good hydrophilicity and water solubility.Using EDC chemistry, the carboxyl group (-COOH) of another PEG terminal reacts with a primary amine group, thus, PEG DSPE can be easily incorporated into liposomes and other nanoparticles through the reaction of carboxylic acid and amine.

phospholipid PEG carboxyl (DSPE-PEG-COOH), (DSPE) conjugated polyethylene glycol is a combination of phospholipids and polyethylene glycol with hydrophilic and hydrophobic properties.Polyethylene glycol phospholipid liposomes form high-quality materials for drug delivery, gene transfection, and vaccine delivery.These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies, polypeptides.The carboxyl group (-COOH) can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group.

Four, related products

phospholipid-polyethylene glycol-carboxyl, DSPE-PEG-COOH, DSPE-PEG-Acid, MW: 20000, CAS: 1403744-37-5

phospholipid-polyethylene glycol-carboxyl, DSPE-PEG-COOH, DSPE-PEG-Acid, MW: 10000, CAS: 1403744-37-5

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phospholipid-polyethylene glycol-carboxyl, DSPE-PEG-COOH, DSPE-PEG-Acid, MW: 3400, CAS: 1403744-37-5

phospholipid-polyethylene glycol-carboxyl, DSPE-PEG-COOH, DSPE-PEG-Acid, MW: 1000, CAS: 1403744-37-5

Four-arm-polyethylene glycol-phospholipid, 4-Arm PEG-DSPE, MW: 20000

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Four-arm-polyethylene glycol-phospholipid, 4-Arm PEG-DSPE, MW: 3400

Four-arm-polyethylene glycol-phospholipid, 4-Arm PEG-DSPE, MW: 1000