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Chinese and English instructions prosci LAG-3 recombinant protein
2022-07-07 07:10:00 【Sylvia_ sc】
Targeting inhibitory co receptors PD-1 and CTLA-4 Checkpoint immunotherapy has revolutionized cancer treatment , and LAG-3 As a new generation of inhibitory checkpoints , It is expected to be used in cancer treatment J Promising targets .
AI Meijie ProSci LAG-3 Chemical properties of recombinant protein :
English name :LAG-3 Recombinant Protein
cat#:PSI-90-241
specifications :50ug
Source host :CHO cells
Dissolution suggestion : Before opening the cover , Centrifugation first . It is recommended to dissolve and use in the way required in the instructions .
Save suggestions :Stable for at least 6 months after receipt when stored at -20˚C.
species : human beings
Source species : Human cells
Recombinant protein sequence :Leu23-Gly434
Fusion label :C-6 his label
AI Meijie ProSci LAG-3 Recombinant protein It can be applied to application types that have been tested and verified .
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Specications:
Species Human, Monkey, Mouse
Source Species CHO cells
Fusion Tag Fc Tag
Biological Activity
Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic
cells.
Properties:
Purity
>99% (SDS-PAGE).<br><br> Endotoxin level is less than 0.1EU/ μg puried protein (LAL test;
Lonza).
Physical State Liquid
Buer In PBS.
Concentration 0.5 mg/ml
Storage Conditions Stable for at least 6 months after receipt when stored at -20°C.
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