Chinese and English instructions prosci LAG-3 recombinant protein

Targeting inhibitory co receptors PD-1 and CTLA-4 Checkpoint immunotherapy has revolutionized cancer treatment , and LAG-3 As a new generation of inhibitory checkpoints , It is expected to be used in cancer treatment J Promising targets .

AI Meijie ProSci LAG-3  Chemical properties of recombinant protein ：

English name ：LAG-3 Recombinant Protein

cat#：PSI-90-241

specifications ：50ug

Source host ：CHO  cells

Dissolution suggestion ： Before opening the cover , Centrifugation first . It is recommended to dissolve and use in the way required in the instructions .

Save suggestions ：Stable for at least 6 months after receipt when stored at -20˚C.

species ： human beings

Source species ： Human cells

Recombinant protein sequence ：Leu23-Gly434

Fusion label ：C-6 his label

AI Meijie ProSci LAG-3 Recombinant protein It can be applied to application types that have been tested and verified .

 

Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

Specications：

Species Human, Monkey, Mouse

Source Species CHO cells

Fusion Tag Fc Tag

Biological Activity

Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic

cells.

Properties：

Purity

>99% (SDS-PAGE).<br><br> Endotoxin level is less than 0.1EU/ μg puried protein (LAL test;

Lonza).

Physical State Liquid

Buer In PBS.

Concentration 0.5 mg/ml

Storage Conditions Stable for at least 6 months after receipt when stored at -20°C.