Abnova maxpab mouse derived polyclonal antibody solution

AI Meijie  Abnova METTL3  purification  MaxPab  Mouse polyclonal antibody  (B01P) —— For full-length humans  METTL3  Mouse polyclonal antibody produced by protein .

AI Meijie  Abnova MaxPab Chemical properties of polyclonal antibody from mice ：

Immunogen ：METTL3 (NP_062826.2, 1 aa ~ 580 aa)  Full length human protein .

host ： rat

Reactivity ： human beings

Interspecific antigen sequence ： mouse  (97);  Rat  (96)

Quality control testing ： Antibodies that are reactive to mammalian transfected lysates .

Storage buffer ： stay  1x PBS  in ,pH 7.4

Storage instructions ： Stored in the  -20°C  Or lower . Repack to avoid repeated freezing and thawing .

AI Meijie  Abnova MaxPab  Mice Source Polyclonal antibody Application ：

On the left ： Western blotting （ Tissue lysates ）

METTL3 MaxPab  Polyclonal antibody . In human colon  METTL3  Western blot analysis of expression .

Chinese ：Western Blot（ Transfection lysate ）

adopt  METTL3 MaxPab  The effect of polyclonal antibody on transfection  293T  Cell line  ( H00056339-T01 ) Medium  METTL3  Expression was analyzed by Western blot .

lane  1：METTL3  Transfected lysates （63.8 KDa）.

lane  2： Untransfected lysates .

Right picture ： Immunofluorescence

HeLa  Cellular targeting  METTL3 Purification of MaxPab  Immunofluorescence of antibodies .[ Antibody concentration 10 ug/ml]

Abnova MaxPab  Mice Source Polyclonal antibody Some references ：

1.Relaxed initiation pausing of ribosomes drives oncogenic translation.

Leiming Dong, Yuanhui Mao, Aidong Zhou, Xiao-Min Liu, Jun Zhou, Ji Wan, Shu-Bing Qian.Sci Adv. 2021 Feb 17;7(8):eabd6927. doi: 10.1126/sciadv.abd6927. Print 2021 Feb.

2.m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2.

Mao Y, Dong L, Liu XM, Guo J, Ma H, Shen B, Qian SB.Nat Commun. 2019 Nov 25;10(1):5332. doi: 10.1038/s41467-019-13317-9.

3.Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.

Tsai K, Courtney DG, Cullen BR.PLoS Pathog. 2018 Feb 15;14(2):e1006919. doi: 10.1371/journal.ppat.1006919. eCollection 2018 Feb.