FFA and ICGA angiography

Type of angiography	Contrast object	Anatomy	Structure Vascular proliferation
FFA( Sodium fluorescein )	Retinal vessels	The fundus oculi
ICGA( Indocyanine green )	Choroid	Extrabulbar

Some patients go to experts , The expert replied that there was no hyperplasia , Let's keep observing 、 Follow up regularly .

Then the patient went back happily ,

What's going on here ？

This is because fluorescein angiography shows no leakage , If there is penetration （ It is most likely caused by neovascularization ） It's time to damage the photosensitive layer .

So at this point , It's best to control yourself in advance （ For example, anti vegf Relevant diet, etc ）

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chart 1：  Left for FFA Images , It can be seen that there is only a small amount of fluorescent leakage in the macular area , The lack of CNV Typical performance ; The right to ICGA Images , It can clearly show pigment epithelium detachment and CNV ingredients , Provide richer information for disease diagnosis .

chart 2：  Heidelberg HRA

chart 3: wAMD In patients with FFA+ICGA Early image of synchronous angiography

chart 4: wAMD In patients with FFA+ICGA Synchronous late imaging

chart 5: FFA+ICGA Early display of synchronous angiography PCV Abnormal branch vascular network and polypoid lesions

chart 6:  Another patient ICGA+OCT：ICGA The location of polypoid lesion in OCT There are many pigment epithelium detachment （PED）,PED Incisure （ White arrow ） And for polyps PED peak （ Inverted triangle ） It can be called “ Thumb sign ”[2].